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《DIC彌漫性血管內凝血-北京協和醫院血液科》專家PPT內容預覽
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《DIC彌漫性血管內凝血-北京協和醫院血液科》專家PPT內容簡介
    Disseminated Intravascular Coagulation
    DIC是一種發生于多種疾病或特殊病理狀態下，人體凝血系統被激活而引起中小血管內彌漫性微血栓形成及繼發性纖溶亢進的綜合征。
    由于DIC發展過程中出現不同程度的血小板和凝血因子水平消耗性減少，也稱之為“消耗性凝血病”或“消耗性血栓出血性疾病”。

    Clinical conditions associated with DIC 
    1. Sepsis/Severe infection --- -------- 44.6%
    2. Malignancy ------------------------- 20.7%
    Solid tumors 6.9%，AL 13.8%. Occurrence in APL 37~65%. 
    3. Obstetrical calamities ------------ 13.4%
    Amniotic fluid embolism, Abruptio placentae, Dead fetus
    4. Trauma / Surgery ----------------- 7.4% 
    5. Severe hepatic failure ------------ 7.4% 
    6. Vascular abnormalities
    Kasabach-Merritt syndrome，Large vascular aneurysms
    7. Organ destruction (e.g., severe pancreatitis)
    8. Severe toxic or immunologic reactions
    Snake bites，Recreational drugs，Transfusion reactions，Transplant rejection

    Mortality
    DIC----Death Is Coming.
    Mortality ranges from 31~86%, whether or not heparin was administrated.
    Correlated Factors:
    Underlying disorders
    The extent of orgon dysfuction
    The degree of hemostatic failure
    Increasing age

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